Single kempen

Posted by / 12-Dec-2017 17:48

Single kempen

More lesions were seen on FA than on clinical examination.As the disease progresses damage to the RPE occurs and FA demonstrates punctate RPE window defects.Bilateral white-yellow chorioretinal lesions usually 100-200 microns diameter develop at the level of the inner choroid and retinal pigment epithelium (RPE) which rarely extend to the midperiphery and are never associated with vitritis.They are bilateral in 80% of cases but are usually asymmetric.Pericyte-poor neovascular units have been shown to be more susceptible to one type of treatment (anti-VEGF agents) than pericyte-rich ones.

In addition, several choroidal vessels demonstrated localized points of hyperfluorescence situated close to the vessel wall/border.The initial visual acuity at presentation varies from 20/50 to 20/400.In the original report by Watzke et al, 8 of 12 eyes had VA of 20/50 or better (66.7%), 2 had 20/70, one had 20/500, and another had counting fingers.Over time the newer vessels linked to form a larger neovascular complex with multiple feeder vessels originating from individual neovascular buds.The subsequent fibrotic response lead to a dumbbell-shaped pattern of subretinal fibrosis Indocyanine green (ICG) Indocyanine green (ICG) shows multiple midphase hypofluorescent lesions in the peripapillary posterior pole, corresponding to those seen on exams. It has been reported to show subclinical hypofluorescent spots in 32% of affected eyes, thereby increasing the diagnostic potential in patients who have evaded clinical diagnosis.

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